Quick answer
Each summary explains one area of research: who was studied, what was found, and how much weight the result deserves. We include the limitations of every study and, where they exist, trials that found no benefit. The summaries are educational and not a promise of results.
We summarize published clinical studies in plain English, with a link to PubMed for every one. More summaries are available in Spanish.
- Stem Cells for Knee Osteoarthritis: What Clinical Trials Found
A 2026 meta-analysis of 28 randomized trials and a placebo-controlled phase IIb trial studied mesenchymal stem cell injections for knee osteoarthritis. Here is what they found. - Wharton's Jelly Stem Cells for Knee Osteoarthritis: Clinical Trials
A randomized trial with 26 patients and a meta-analysis of 3 trials studied umbilical cord (Wharton's jelly) mesenchymal stem cells for knee osteoarthritis. Here is what they found. - Exosomes for Wrinkles and Sun-Damaged Skin: What Clinical Studies Found
A 2026 meta-analysis of 39 studies and a 60-person split-face trial studied exosome-based therapies for wrinkles and photoaging. Here is what they found. - Fibroblast Therapy for Smile Lines: What Clinical Trials Found
A double-blind trial with 372 patients and a phase III trial with 215 patients studied fibroblast injections for nasolabial folds and facial contour. Here is what they found. - Stem Cell-Derived Products for Hair Loss: What Clinical Studies Found
A double-blind trial with 38 patients and a 2024 meta-analysis studied stem cell extracts and conditioned medium for androgenetic alopecia. Here is what they found. - Stem Cells for Diabetic Foot Ulcers: What Clinical Studies Found
A randomized trial with 28 patients and a 2025 meta-analysis of 6 trials studied mesenchymal stem cells for diabetic foot ulcers. Here is what they found. - Stem Cells and Exosomes for Lung Disease: Studies That Found Improvement
Clinical trials of mesenchymal stem cells and exosomes in severe COVID-19, pulmonary fibrosis and COPD: what improvement they found, with real numbers and their limits.
Where the evidence is negative
Large, well-controlled trials found no benefit of cell therapies in several conditions, including autism (a Duke University trial with 180 children), ALS (a phase 3 trial) and heart failure (the DREAM-HF trial with 565 patients). That's why Longevity Clinic doesn't offer cell therapies for neurological diseases. Read the overview in stem cell therapy in Mexico.